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Inositol-trisphosphate 3-kinase : ウィキペディア英語版
Inositol-trisphosphate 3-kinase

In enzymology, an inositol-trisphosphate 3-kinase () is an enzyme that catalyzes the chemical reaction
:ATP + 1D-myo-inositol 1,4,5-trisphosphate \rightleftharpoons ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
Thus, the two substrates of this enzyme are ATP and 1D-myo-inositol 1,4,5-trisphosphate, whereas its two products are ADP and 1D-myo-inositol 1,3,4,5-tetrakisphosphate.
This enzyme participates in 3 metabolic pathways: inositol phosphate metabolism, calcium signaling pathway, and phosphatidylinositol signaling system. This enzyme has at least one effector, Calcium.
== Nomenclature ==

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase. Other names in common use include 1D-myo-inositol-trisphosphate 3-kinase, and Ins(1,4,5)P3 3-kinase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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